Metalloproteinases in Inflammatory Bowel Diseases
نویسندگان
چکیده
منابع مشابه
Degradomics of matrix metalloproteinases in inflammatory diseases.
Organisms have evolved to react to stress, tissue damage and pathogen invasion to assure their survival. Leukocytes are the primary responders and they regulate repair, immune defense and inflammation with the aid of a wide variety of other cells (e.g. epithelial, fibroblasts). To assure proper responses, a plethora of proteins are involved including signaling molecules, chemokines and protease...
متن کامل[Inflammatory bowel diseases]
OBJECTIVE: To present a review about inflammatory bowel diseases in childhood so that pediatricians become familiar with two diseases (ulcerative colitis and Crohn s disease) that are increasing in incidence. METHODS: Articles of specific gastroenterological journals were analyzed. Information was also obtained from the author s extensive professional experience in the area. RESULTS: The two di...
متن کاملInflammatory bowel diseases.
All rights reserved. Unless special permission in writing is obtained, no part of this publication may be reproduced, stored in a retrieval system, or be transmitted in any form or by any means, electronic, mechanical, photocopying or otherwise. The material contained in this issue was submitted as previously unpublished material, except in the instances in which credit has been given to the so...
متن کاملChemokines in inflammatory bowel diseases.
Uncontrolled activation of mucosal effector cells has been identified as the main pathogenic mechanism involved in the initiation and perpetuation of mucosal inflammation in inflammatory bowel diseases (IBD). The sustained activation of these cells leads to the aberrant production of various pro-inflammatory mediators, which co-ordinated action amplifies the inflammatory process. In this settin...
متن کاملInflammatory Bowel Diseases Journal
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ژورنال
عنوان ژورنال: Journal of Inflammation Research
سال: 2021
ISSN: 1178-7031
DOI: 10.2147/jir.s288280